Skin toxicity following radiotherapy

radiotherapy tolerance tests

Radiation therapy can cause skin toxicities, but it is important to understand that this does not concern all patients. Indeed, the risk depends on the area to be irradiated and the dose deposited on the skin.. Specifically, the dose to the skin is higher in patients receiving radiotherapy for breast or ENT cancer than in patients undergoing radiotherapy for lung or pancreatic cancer.

Acute side effects are likely to appear from the third week of treatment. These acute side effects manifest generally as dermatitis that corresponds to an inflammation of the skin resulting in erythema (redness),almost like a sunburn. This can cause burning, tingling or itching.. Sometimes, oozing also is observed (exudative erythema). At a more advanced stage, there may be scaling. To prevent this, it is important to follow the suggestions given by the radiation oncologist and nurses (no tight clothes, no deodorant/cream/make-up on the area to be irradiated). The risk of skin side effects may be increased by the concomitant administration of some chemotherapy treatments or targeted therapies.

Much more rarely, some patients will develop skin retraction, called fibrosis, several months or years after treatment(late side effect).. Depending on its severity, this can be more or less disabling.

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Team NovaGray

NovaGray develops radiotherapy tolerance tests for breast and prostate cancer patients. NovaGray's mission is to help personalize cancer treatment by assessing each patient's individual sensitivity before starting radiotherapy. NovaGray technology has been validated by multi-center prospective clinical trials. NovaGray tests are recommended by the French Society of Radiation Oncology (SFRO).